From: Open Veterinary Journal:
Adjuvant electrochemotherapy with bleomycin and cisplatin combination for
canine soft tissue sarcomas: A study of 30 cases
Enrico P. Spugnini, Bruno Vincenzi, Bruno Amadio and Alfonso Baldi
Biopulse srl, Naples, Italy 2
Medical Oncology Department, University Campus Bio-Medico of Rome, Rome, Italy 3
SAFU service, Regina Elena Cancer Institute, Rome, Italy 4
Department of Environmental, Biological and Pharmaceutical Sciences and Technologies Campania University
“Luigi Vanvitelli”, Caserta, Italy 5
Institute of Biosciences and BioResources, CNR, Naples, Italy
Abstract
Electrochemotherapy (ECT) couples the administration of anticancer drugs with the delivery of electric pulses that increase the drug uptake through the cell membranes, thus resulting in an improved efficacy. This study has evaluated the tolerability and efficacy of the combination of systemic bleomycin and local cisplatin as ECT agents for incompletely excised canine soft tissue sarcoma (STS)…